মঙ্গলবার, ৩০ এপ্রিল, ২০১৩

Laser Mountain Played Laser Tag Onstage With Nerf Guns, Android Phones And A Node.js Server

P1010633Carson Britt and Matthew Drake convinced everyone with their onstage demo of Laser Mountain at the Disrupt NY Hackathon. They attached Android phones to the Nerf guns (that TechCrunch gave away yesterday) to recreate a laser tag game with a real-time score server. After receiving the Nerf guns, they started working right away on Laser Mountain. “We already had the domain name lasermoutain.com, so we didn’t have a choice,” Britt said. When asked why they bought this domain, Drake answered, “I pick up domains all the time.” The Android phones track movements using the built-in gyroscopes and then transmit the information to a Node.js server. To register when someone is firing, they use the phone’s microphones and the Nerf gun’s loud firing noise. Last night, the team of two didn’t sleep at all to finish their hack on time for the onstage demo. It wasn’t their first hackathon but it was the first time at the Disrupt Hackathon. But it’s not the end for Laser Mountain. “We are going to Kickstarter it,” Drake said. With fewer than 24 hours of development, the team is certainly talented enough to succeed. You should watch the two developers play laser tag onstage:

Source: http://feedproxy.google.com/~r/Techcrunch/~3/cPLlcf1NlpU/

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When He Talks Abortion President Obama Pretends to Be a Libertarian (Atlantic Politics Channel)

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সোমবার, ২৯ এপ্রিল, ২০১৩

Mini-stroke could limit Algeria president ambition

Algerian President Abdelaziz Bouteflika, right, shakes hands with his South African counterpart Jacob Zuma as they pose for photographers prior to their meeting at the presidential palace in Algiers, Algeria, Monday, April 15, 2013. (AP Photo/Anis Belghoul)

Algerian President Abdelaziz Bouteflika, right, shakes hands with his South African counterpart Jacob Zuma as they pose for photographers prior to their meeting at the presidential palace in Algiers, Algeria, Monday, April 15, 2013. (AP Photo/Anis Belghoul)

(AP) ? The mini-stroke suffered by Algeria's president has cast fresh doubt on his perceived ambition to run for a fourth term next year as leader of one of Africa's largest and richest countries.

The possibility that President Abdelaziz Bouteflika, 76, could step down could affect the stability of this key U.S. ally in the fight against terror but might also open up its long-stagnant politics.

Bouteflika on Saturday had a brief blockage of a cerebral blood vessel known as a transient ischemic attack, which authorities said he quickly recovered from and had no lasting complications. He was sent to a military hospital in Paris for tests, however, and remained there Sunday night.

Algeria's state news agency has been uncommonly open about the president's latest health problem but insisted he will be back to work soon.

"He has not had any lasting damage and no motor or sensory function has been impaired," Rachid Bougherbal, the director of the institute of sports medicine, told the state news agency.

Such mini-strokes ? known as TIAs ? have symptoms of confusion and disorientation. They are quite brief but can re-occur. In a third of the cases, a full stroke can happen within a year, according to the American Stroke Association.

The mini-stroke has come during a delicate time in Bouteflika's 14-year-reign, as rumors over his poor health have proliferated and he has rarely appeared in public.

Charges of corruption have also dogged his administration. Terrorist groups, including one that carried out a massive attack on an Algerian gas field in January, are also known to be in remote desert areas along Algeria's borders.

There has also been a great deal of social unrest in this North African nation of 37 million, especially over Algeria's high unemployment rate.

Despite announcing that he would step down at the next presidential election, it is widely believed that Bouteflika wants to run for a fourth term in April 2014.

So convinced are residents of this unspoken desire of the president that there has been no talk of other candidates, only when he will make his announcement.

"This totally ends the chances of his fourth term," said Chafik Mesbah, a political analyst and former member of the military intelligence.

"This is ultimately a good thing," he added, explaining that the army and the intelligence services were increasingly upset over the rising tide of corruption.

Bouteflika's last term has seen a proliferation of corruption charges that have embroiled many of his former ministers and associates, mostly revolving around bribes paid by foreign companies to win lucrative oil or infrastructure contracts.

The charges had even reached up to the president's brother, Said Bouteflika, who had been amassing power as the leader's main adviser until he was forced to resign.

Even before the latest scare, the president's diminished health had been slowing down the pace of government, said analyst Mohammed Saidj.

"The council of ministers, which is an important institution for transmitting laws, hasn't met since December," he said. "All these absences can only be explained by one thing: his health doesn't allow him to assume the full duties of the president."

Bouteflika was elected in 1999 to a country with a devastated economy that had been savaged by years of civil war with Islamists. He is widely credited with ending the war and putting the country back on its feet, aided by soaring energy prices.

Algeria weathered the 2011 Arab Spring protests partly because of a lack of organized opposition but also because of massive sums spent on increasing subsidies and raising salaries to keep residents happy.

But as his health has declined, Bouteflika has become a shadow of his former energetic self when he was the world's youngest foreign minister in 1963 after Algeria won independence from France and became one of the faces of the non-aligned movement.

He doesn't seem to be ready, however, to let the next generation take over.

University of Algiers political professor Rachid Tlemcani said, like most authoritarian rulers, "he wishes to die in power."

But Tlemcani says Bouteflika stepping down would be a good thing for Algeria.

"I think the political game would be open, which would be really good," he said. "It can only be positive for Algeria ? the game has been very closed so far."

Life on the streets of Algiers, the capital, went on as usual the day after the president's health scare. Most people seemed more focused on the country's upcoming soccer club final.

Walking through Algiers' El Biar neighborhood, Achou Slimani shrugged.

"It's normal that he fell sick, it's not the first time," he said. "He was already sick, he recovered, he came back."

______

Associated Press writer Aomar Ouali contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-04-28-Algeria-President-Stroke/id-a4792c79ccc74021aec212dd11b44e27

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রবিবার, ২৮ এপ্রিল, ২০১৩

WH: Anthony Foxx in line for transportation post (The Arizona Republic)

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Mother of Boston Marathon bomb suspects found deeper spirituality

BOSTON (AP) ? In photos of her as a younger woman, Zubeidat Tsarnaeva wears a low-cut blouse and has her hair teased like a 1980s rock star. After she arrived in the U.S. from Russia in 2002, she went to beauty school and did facials at a suburban day spa.

But in recent years, people noticed a change. She began wearing a hijab and cited conspiracy theories about 9/11 being a plot against Muslims.

Now known as the angry and grieving mother of the Boston Marathon bombing suspects, Tsarnaeva is drawing increased attention after federal officials say Russian authorities intercepted her phone calls, including one in which she vaguely discussed jihad with her elder son. In another, she was recorded talking to someone in southern Russia who is under FBI investigation in an unrelated case, U.S. officials said.

Tsarnaeva insists there is no mystery. She's no terrorist, just someone who found a deeper spirituality. She insists her sons ? Tamerlan, who was killed in a gunfight with police, and Dzhokhar, who was wounded and captured ? are innocent.

"It's all lies and hypocrisy," she told The Associated Press in Dagestan. "I'm sick and tired of all this nonsense that they make up about me and my children. People know me as a regular person, and I've never been mixed up in any criminal intentions, especially any linked to terrorism."

Amid the scrutiny, Tsarnaeva and her ex-husband, Anzor Tsarnaev, say they have put off the idea of any trip to the U.S. to reclaim their elder son's body or try to visit Dzhokhar in jail. Tsarnaev told the AP on Sunday he was too ill to travel to the U.S. Tsarnaeva faces a 2012 shoplifting charge in a Boston suburb, though it was unclear whether that was a deterrent.

At a news conference in Dagestan with Anzor last week, Tsarnaeva appeared overwhelmed with grief one moment, defiant the next. "They already are talking about that we are terrorists, I am terrorist," she said. "They already want me, him and all of us to look (like) terrorists."

Tsarnaeva arrived in the U.S. in 2002, settling in a working-class section of Cambridge, Mass. With four children, Anzor and Zubeidat qualified for food stamps and were on and off public assistance benefits for years. The large family squeezed itself into a third-floor apartment.

Zubeidat took classes at the Catherine Hinds Institute of Esthetics, before becoming a state-licensed aesthetician. Anzor, who had studied law, fixed cars.

By some accounts, the family was tolerant.

Bethany Smith, a New Yorker who befriended Zubeidat's two daughters, said in an interview with Newsday that when she stayed with the family for a month in 2008 while she looked at colleges, she was welcomed even though she was Christian and had tattoos.

"I had nothing but love over there. They accepted me for who I was," Smith told the newspaper. "Their mother, Zubeidat, she considered me to be a part of the family. She called me her third daughter."

Zubeidat said she and Tamerlan began to turn more deeply into their Muslim faith about five years ago after being influenced by a family friend, named "Misha." The man, whose full name she didn't reveal, impressed her with a religious devotion that was far greater than her own, even though he was an ethnic Armenian who converted to Islam.

"I wasn't praying until he prayed in our house, so I just got really ashamed that I am not praying, being a Muslim, being born Muslim. I am not praying. Misha, who converted, was praying," she said.

By then, she had left her job at the day spa and was giving facials in her apartment. One client, Alyssa Kilzer, noticed the change when Tsarnaeva put on a head scarf before leaving the apartment.

"She had never worn a hijab while working at the spa previously, or inside the house, and I was really surprised," Kilzer wrote in a post on her blog. "She started to refuse to see boys that had gone through puberty, as she had consulted a religious figure and he had told her it was sacrilegious. She was often fasting."

Kilzer wrote that Tsarnaeva was a loving and supportive mother, and she felt sympathy for her plight after the April 15 bombings. But she stopped visiting the family's home for spa treatments in late 2011 or early 2012 when, during one session, she "started quoting a conspiracy theory, telling me that she thought 9/11 was purposefully created by the American government to make America hate Muslims."

"It's real," Tsarnaeva said, according to Kilzer. "My son knows all about it. You can read on the Internet."

In the spring of 2010, Zubeidat's eldest son got married in a ceremony at a Boston mosque that no one in the family had previously attended. Tamerlan and his wife, Katherine Russell, a Rhode Island native and convert from Christianity, now have a child who is about 3 years old.

Zubeidat married into a Chechen family but was an outsider. She is an Avar, from one of the dozens of ethnic groups in Dagestan. Her native village is now a hotbed of an ultraconservative strain of Islam known as Salafism or Wahabbism.

It is unclear whether religious differences fueled tension in their family. Anzor and Zubeidat divorced in 2011.

About the same time, there was a brief FBI investigation into Tamerlan Tsarnaev, prompted by a tip from Russia's security service.

The vague warning from the Russians was that Tamerlan, an amateur boxer in the U.S., was a follower of radical Islam who had changed drastically since 2010. That led the FBI to interview Tamerlan at the family's home in Cambridge. Officials ultimately placed his name, and his mother's name, on various watch lists, but the inquiry was closed in late spring of 2011.

After the bombings, Russian authorities told U.S. investigators they had secretly recorded a phone conversation in which Zubeidat had vaguely discussed jihad with Tamerlan. The Russians also recorded Zubeidat talking to someone in southern Russia who is under FBI investigation in an unrelated case, according to U.S. officials who spoke on condition of anonymity because they were not authorized to discuss the investigation with reporters.

The conversations are significant because, had they been revealed earlier, they might have been enough evidence for the FBI to initiate a more thorough investigation of the Tsarnaev family.

Anzor's brother, Ruslan Tsarni, told the AP from his home in Maryland that he believed his former sister-in-law had a "big-time influence" on her older son's growing embrace of his Muslim faith and decision to quit boxing and school.

While Tamerlan was living in Russia for six months in 2012, Zubeidat, who had remained in the U.S., was arrested at a shopping mall in the suburb of Natick, Mass., and accused of trying to shoplift $1,624 worth of women's clothing from a department store.

She failed to appear in court to answer the charges that fall, and instead left the country.

___

Seddon reported from Makhachkala, Russia. Associated Press writers Eileen Sullivan and Matt Apuzzo contributed to this report from Washington.

Source: http://news.yahoo.com/mother-bomb-suspects-found-deeper-spirituality-224317582.html

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IRIScan Mouse


Scanners and mice are more similar than you might expect. Just as a mouse can sweep the breadth and height of an on-screen page, a device like a wand scanner can capture images of physical documents as it sweeps across lines or blocks of text. The IRIScan Mouse merges the two devices. You can use it as a mouse, and with a click of a button you can scan a physical document, OCR it, save it in various formats, or send it to social media or the Cloud.

The Mouse Scanner as a Mouse
The IRIScan Mouse is a wired mouse, connecting to a computer's USB port. The device is reasonably attractive, black (glossy on top, matte on the sides and bottom) with green trim. The Scan button, on the left side, glows blue, and blinks when a scan is in progress. On the bottom of the mouse is a plastic window through which the scan element can read the page. A flickering white light illuminates the page while you're scanning.

I've used the IRIScan Mouse as my normal work mouse for about a week, and in that capacity?in terms of scrolling and doing other typical mouse tasks?it's operated smoothly, with only a single issue of note. The scan button is on the left side of the mouse, right where I rest the ball of my thumb. The scan button requires a bit of pressure to activate, but nonetheless I've triggered it accidentally while writing a review or working in a Word document. Doing so is an annoyance, as it takes a few moments to stop and then cancel the scan. It happens most frequently when I'm standing at my test bench taking notes, though I've also accidentally initiated scans while typing at my desk.

Software
The scanning software comes on an included disk, which you install on your PC (it is Windows only). Software includes IRISCompressor, which enables compression of image and PDF files. You can send notes to Evernote?the IRIScan Mouse includes 3 free months of Evernote Premium. You can also send scanned text directly to Google Translate. Output formats include PNG, JPEG, TIFF, BMP, PDF, XML, and DOC.

Scanning With the Mouse
To scan, you place the mouse on a document, press the scan button, and sweep the mouse across the parts of the document you want to scan. As you scan a larger area, the view will automatically zoom out. You'll want to have plenty of free room to the sides of the document if you want to scan the whole thing. I found the scanning process awkward, as tracking wasn't that great.

When you're done scanning, you press the scan button again; the scan will appear rectangular and properly aligned. The Edit menu will appear; you can Paste the scan (either as image or text); Share (to email, Facebook, Twitter, or Flickr); send it to Apps (Evernote or Google Translate); Save (to the file formats mentioned below); Print; Edit; or access Settings.

When you paste a scan as text to a program like Word, the IRIScan software will perform text recognition on it, a quick process. Then you can edit or save the document. OCR performance was a mixed bag. It read our Arial test page at sizes down to 8 points without a mistake, but with Times New Roman it had some errors at all sizes up to 12 points.

The IRIScan Mouse is best for scanning individual sheets of paper; scanning from a magazine proved tricky at times as the text wouldn't always stay flat enough for a clean scan. Also, since the scan window is on the left side of the mouse, it was hard (and sometimes impossible) to scan to the inner margin on left-handed pages.

For about $50 more than you'd pay for a normal wired mouse, you can get the IRIScan Mouse, a wired (USB-connected) mouse that can scan to text or image, provides text recognition, and can save scanned documents to various formats as well as perform as a typical mojuse. It's best for occasional, light-duty scanning of documents or images. The scanner portion is most akin to a wand scanner such as the Editors' Choice VuPoint Solutions Magic Wand Wi-Fi PDSWF-ST44-VP . However, most wand scanners operate PC-free, while the IRIScan Mouse doesn't.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/y9kosRXKU-M/0,2817,2418230,00.asp

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E! live at White House Correspondents' Dinner. Is that good for journalism?

The White House Correspondents' Dinner, a scholarship and awards event for journalists, has become a star-studded, glitzy, and E!-friendly bash. Some fear it's sending the wrong message.

By Husna Haq,?Correspondent / April 26, 2013

Kris Jenner (l.) with Sofia Vergara (c.) and Kim Kardashian during the White House Correspondents' Association Dinner last year, in Washington. The White House Correspondents' Dinner has become more of a star-studded, glitzy, Hollywood East elite, inside-the-Beltway bash than a scholarship and awards dinner for journalists.

Haraz N. Ghanbari/AP

Enlarge

Nerd prom??Ha. The White House Correspondents? Dinner is as much a nerd prom as the Super Bowl is a tailgate party.

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It?s more of a star-studded, glitzy, Hollywood East elite, inside-the-Beltway bash than a scholarship and awards dinner for journalists.

It?s not for naught that veteran TV journalist Tom Brokaw, who stopped attending the dinner some years ago, turned down an invitation to this year?s gala Saturday night.

?The breaking point for me was Lindsay Lohan,? he told Politico recently of his becoming an outspoken critic of the event last year.??What we?re doing with that dinner, as it has been constituted for the past several years,? he added, ?is saying, ?We?re Versailles. The rest of you eat cake.? ?

Ouch.

The White House Correspondents' Association (WHCA) is a tax-exempt nonprofit that has actually awarded hundreds of thousands of dollars in scholarships to budding journalists since 1991. Last year it awarded 16 college students $132,200 in scholarships.

But let?s be honest. We all know what this is really about: the celeb-studded guest list, the red carpet, the entertainment, and yes, the after-parties. (At least a dozen media organizations, from Vanity Fair to Bloomberg Media to MSNBC, host chichi after-parties in such venues as the French and Italian embassies.)

Oh, and the money. In 2010, the latest year for which tax records are available for the organization, the WHCA spent $432,443 on the shindig, including $378,092 on renting the facility (the swanky Washington Hilton) and associated costs. Media organizations drop $2,750 per table of 10.

But, as the Washington Post points out, that?s small change. When you count the before- and after-parties, some media groups will dole out as much as $200,000 on the weekend?s activities.

You know it?s gotten out of hand when corporate underwriters are called in to sponsor some of the media-hosted after-parties. Starbucks, Ben & Jerry?s, Smartwater, and Bacardi will provide the refreshments at MSNBC?s party. Five corporate sponsors, including Mercedez-Benz and Corona Light, were listed on the invitation for an event hosted by Capitol File magazine.

But this, we think, is when things hit rock bottom. For the first time in White House Correspondents? Dinner history, E! Entertainment network announced that it will livestream the red carpet at the so-called nerd prom. What an honor. Like when Kim Kardashian offers to write the forward for your book on the Armenian genocide.

Sure, we know what some of you are thinking: Loosen up, let go. The White House Correspondents? Dinner long ago gave up pretending that it?s a serious affair.

But here?s the thing. Like financial institutions, media organizations rely on their reputations in exchange for reader trust and credibility. And it?s no secret that the media?s credibility is under perennial siege. (Some 60 percent of Americans said they had little or no trust in mass media, according to a Sep. 2012 Gallup poll cheerfully titled "US Distrust in Media Hits New High.")

In other words, the media need a White House Correspondents? Dinner like Donald Trump needs self-esteem training.

As Brokaw said about the White House Correspondents? Dinner on ?Meet the Press? in May 2012, ?If there?s ever an event that separates the press from the people it?s supposed to serve, symbolically, it?s that one. It is time to rethink it.?

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/cBgDgOkCmTI/E!-live-at-White-House-Correspondents-Dinner.-Is-that-good-for-journalism

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শনিবার, ২৭ এপ্রিল, ২০১৩

Remote Canadian town hosts oil at heart of Keystone controversy

The Keystone pipeline, a project to transport heavy crude from Canada to the Gulf Coast, is expected to provide hundreds of temporary construction jobs in the U.S., but critics say the oil it carries comes at a terrible cost. NBC's Anne Thompson reports.

Anne Thompson, chief environmental correspondent, NBC News writes

While the possible construction of the Keystone XL pipeline has made for contentious disagreements from the halls of Congress to ranches in Nebraska, the real environmental debate begins in a place most Americans have never heard of.

Nearly 700 miles north of the U.S.-Canada border sits Fort McMurray, Alberta, the unofficial capital of oil sands country,?and the heart of the Keystone controversy.

Canada's oil reserves rank third largest in the world and sit beneath the vast Alberta forest. Oil mining companies like Shell, Syncrude and Suncor surround the town. They are big industrial operations in an even bigger forest.

Oil here is not the liquid black gold you think of in Texas or Oklahoma or the Gulf of Mexico.? It is a tar-like substance called bitumen.? It is excavated by mining or steam assisted drilling, where it is literally melted a quarter mile beneath the earth.? This oil is so heavy it must be upgraded or diluted before it can transported.


At Shell's jackpot mine in the oil sands, the company digs 24 hours a day, 365 days a year. Twenty-eight trucks burning 45 gallons of diesel fuel an hour transport the goods once lifted from the ground.

The whole operation is a carbon intensive process sending more global warming gases into the atmosphere. How much depends on your point of view.?The oil industry downplays the impact,?but opponents claim it is up to 37 percent more carbon intensive to produce a barrel of crude from oil sands.

The State Department, in its review of Keystone, says the oil from this area produces 17 percent more greenhouse gasses than conventional crude.?? Those emissions are the heart of the environmental debate in Alberta, and a big reason why opponents call this "dirty oil."

Jeff Mcintosh / AP file

This Sept. 19, 2011 aerial photo shows a tar sands mine facility near Fort McMurray, in Alberta, Canada.

The oil sands industry here plans to more than double its production by 2030. Shell Vice President Tom Purves explains, "We have a massive resource here that's oil from a country that's very stable, it's a democratic country. We're able to transport this oil on pipelines safely to the US and other parts of the world, other parts of North America. And I think we'll be using fossil fuels for a long time - this will be an important part of it."

Opponents say this is not about stopping development. They realize this is a natural resource crucial to Canada's future. For them, it's about the pace, the scale and how it adds to Canada's carbon footprint. They worry approval of the Keystone pipeline will turbo-charge growth.

Eriel Deranger of the Athabasca Chipewyan First Nation understands the booming industry brings modern conveniences. It also brings, she says, modern problems threatening the forest and wildlife that are still part of the First Nations culture and have been for centuries.

"There has to be a balance, and respect for human - fundamental human rights and the rights to human subsistence and survivals. What we're seeing is that balance is out of whack here in Alberta. I think we're seeing development take precedence over the preservation of peoples and people's basic right to human survival," she said.

At the Pembina Institute, an environmental think tank, the focus is about carbon dioxide.? If things continue the way they are, says Jennifer Grant, Pembina's Oil Sands director, Canada will not meet its goals to reduce greenhouse gas emissions.

"Right now between 2005 and 2020, we're expecting 67 million tons of reductions from other sectors in Canada's economy.? During that same timeframe we're expected to see 72 million tons oil sands greenhouse gas emissions growth," Grant said.

Todd Korol / REUTERS file

Oil, steam and natural gas pipelines run through the forest at the Cenovus Foster Creek SAGD oil sands operations near Cold Lake, Alberta, in a July 9, 2012, photo.

Aware of the concerns in Canada and in the U.S. about climate change,?the industry is quick to point out it has reduced carbon emissions intensity ? that is, the emissions created per barrel ??26 percent from 1990 to 2009. But overall emissions are still growing because of increases in production. Shell hopes to have the ability to capture some of the carbon emissions at one of its facilities by 2015.

But there is no perfect way to extract oil. Cenovus, a Canadian company which drills for oil, uses natural gas to make steam. Al Reid, vice president of Cenovus' Christina Lake operation, says reducing the amount of natural gas it burns shrinks the carbon footprint and helps the bottom line. But he admits there's only so much they can do.

"With today's technology, we will not get emissions down to zero. Can we continue to decrease them? I think that's very possible and that's something that we work on every single day," he said. "And over time there may be a technology that allows us to do that but we don't have that technology today."

There's no question the debate in the US over Keystone is having an impact in Canada. This month, Alberta's government floated the idea of raising its price on carbon to force the industry to do more to reduce emissions. Will that be enough to convince President Barack Obama to approve a pipeline that carries oil with a bigger carbon footprint?

It's not just the environment. There are issues of energy security and economic impact. The State Department says the extension would provide 3,900 construction jobs over a? 1 to 2 year period? and another 38,200 positions associated with the construction over the same time frame.? Once built it says the pipeline would create 35 permanent jobs and 15 temporary ones, according to the government study released last month. It is multifaceted issue that will dominate discussion for months to come.

?

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2b3a2dec/l/0Ldailynightly0Bnbcnews0N0C0Inews0C20A130C0A40C260C1793340A20Eremote0Ecanadian0Etown0Ehosts0Eoil0Eat0Eheart0Eof0Ekeystone0Econtroversy0Dlite/story01.htm

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Growth falls short of forecasts, weakness ahead

By Lucia Mutikani

WASHINGTON (Reuters) - The economy regained speed in the first quarter, but not as much as expected, heightening fears it could struggle to cope with deep government spending cuts and higher taxes.

Gross domestic product expanded at a 2.5 percent annual rate, the Commerce Department said on Friday, after growth nearly stalled in the fourth quarter. Economists had expected a 3.0 percent growth pace.

"It wasn't the bang-up start to the year we had hoped for, and the signals from March suggested that we will only decelerate from here," said Avery Shenfeld, chief economist at CIBC World Markets in Toronto.

Growth rebounded in the early part of 2013 but data ranging from employment to retail sales and manufacturing weakened substantially in March. It appears the factory sector slowed further in April and many forecasters expect the economy's softness to persist into the third quarter before a convincing revival emerges, given belt-tightening in Washington.

A 2 percent payroll tax cut expired at the start of the year and $85 billion in mandatory spending cuts, known as the sequester, started to take hold at the beginning of March.

Second-quarter growth is expected to come in around a 1 percent pace, with growth for the full year seen around a sluggish 2 percent, about the same as in the prior three years.

"It certainly seems like we are in store for a significantly lower rate of growth than we saw here in the first quarter," said Sam Bullard, a senior economist at Wells Fargo Securities in Charlotte, North Carolina.

Government spending has already been on a downward path.

In the first three months of the year, it fell at a 4.1 percent pace as defense outlays dropped sharply for a second straight quarter. It has now moved lower in 10 of the last 11 quarters.

"The decline in government spending over the past two quarters is the biggest six-month contraction since the Korean war ended," Paul Ashworth, chief U.S. economist at Capital Economics in Toronto said in a research note.

SUPPORT FOR FED STIMULUS

In the fourth quarter of last year, the economy had expanded at only a 0.4 percent pace.

A big part of the pick-up in activity in the first quarter was due to the filling up of silos by farmers after a drought last summer decimated crop output. Removing inventories, the growth rate was a tepid 1.5 percent, a slowdown from a comparable 1.9 percent in the fourth quarter.

Still, most areas of the economy contributed to growth, with the exception of government, the trade sector and investment by businesses in offices and other commercial buildings.

While consumer spending increased solidly, it came at the expense of saving, which does not bode well for the future.

A separate report showed worries about finances sapped consumer morale in April, offering another potentially troubling harbinger. The Thomson Reuters/University of Michigan's final reading on the overall index on consumer sentiment fell to 76.4 last month from 78.6 in March.

Stocks on Wall Street fell on the data, while prices for Treasury debt rose and the dollar weakened against the yen.

The GDP report, which also showed a deceleration in inflation, provided ammunition for the Federal Reserve to maintain its monetary stimulus. The U.S. central bank, which meets next week, is widely expected to keep purchasing bonds at a pace of $85 billion a month.

"It will give doves the upper hand at next week's Federal Reserve meeting," said Diane Swonk, chief economist at Mesirow Financial in Chicago. "Don't expect to see any tapering of asset purchases or a slowdown in the growth of the Fed's balance sheet anytime soon."

Consumer spending, which accounts for more than two-thirds of U.S. economic activity, rose at a 3.2 percent pace - the fastest since the fourth quarter of 2010.

The increase came despite the higher taxes and steeper gasoline prices. Households, however, had to cut back on saving as incomes dropped at a 5.3 percent rate, the steepest descent since late 2009.

The saving rate - the percentage of disposable income households are socking away - fell to 2.6 percent, the lowest since the fourth quarter of 2007, from 4.7 percent in the final three months of last year.

INFLATION SLOWDOWN

Despite the spike in gasoline prices, inflation pressures were benign. Inflation rose at a 0.9 percent rate, the smallest gain since the second quarter of 2012 and a sharp slowdown from the 1.6 percent pace logged in the fourth quarter.

A core measure that strips out food and energy costs rose at a 1.2 percent rate.

The lack of inflation should come as welcome relief for American households, but it could cause some nervousness at the U.S. central bank, which aims to keep inflation close to 2 percent.

Business spending on equipment and software slowed sharply, and homebuilding also moderated, although it marked an eighth straight quarter of growth. Housing added to GDP last year for the first time since 2005.

While exports rebounded, they were outpaced by a surge in imports, resulting in a trade deficit that cut off half a percentage point from output.

(Editing by Andrea Ricci and Tim Ahmann)

Source: http://news.yahoo.com/growth-falls-short-forecasts-weakness-ahead-045320313.html

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One Today by Google leads Android Apps of the Week

One Today by GoogleThis week brought us a new app from Google that's actively trying to make the world a better place, one day at a time, one dollar at a time. That app is One Today by Google, and it's the top app of the week. We've also got a new voice activated personal assistant, the ultimate travel-log app, a new way to meet people online, and a way to keep your business and personal lives separate, at least as far as phone numbers are concerned.

Google may be a company hell bent on taking over the entire world, but it's always quite possible that they'll be benevolent and merciful new overlords, ushering us into a new age of peace and prosperity! At least, that's what you might conclude thanks to their new app One Today by Google. Probably the most noble app to be put out by such a massive company, One Today brings a different nonprofit group or project to your attention every single day, and asks that you donate one single dollar to the cause, hopefully sharing that donation with social media and getting larger chunks of change to the people who are trying to make the world better. We're all philanthropists in Google's new world order! But seriously. This is great stuff, and I'm glad to see it.


Also on Android Apps

Instead of celebrating Earth Day once a year, adopt an eco-friendly consciousness. Zinio ?s digital newsstand saves 104 thousand trees per month, and here?s how you can get involved.


Speaking of awesome futuristic scenarios that we've all seen in movies, haven't you always wanted your very own AI assistant and companion? Well? Indigo from Artificial Solutions is a pretty close alternative for now. Like the beloved Siri on iOS, Indigo is a voice enabled personal assistant that actually chats back at you. It'll look up directions, let you leave notes and reminders, find restaurants and showtimes, and most importantly, play YouTube videos, let you update Facebook, and also read, tweet, and retweet on Twitter. As with any app this advanced, there are plenty of kinks to work out and bugs to squash, but just because this isn't quite Cortana from the Halo games series doesn't mean it isn't really cool!

The Traveler from Frog Baby Apps is looking to be the ultimate app for documenting any and every vacation you ever take, from family road trips to nowhere USA to gallivanting tours across Europe and the rest. The app will let you record video and take photos, sketch things you see and leave notes, and even record your paths, replaying them and showing any photos, videos, or sketches you take at the context appropriate times. Talk about a literal walk down memory lane. This is a great concept and should definitely be downloaded by anyone who travels with regularity.

People have had to figure out all new ways to date and find that significant other in the Internet age, and 'Swoon: who's crushing on you?' is just the latest in a long line of OKCupids and lesser OKCupids. Breaking things down to a basic level of face shots and primary interests, you can play a little game of 'hot or not' and like or pass on various people in your given area anonymously, and you can even message each other in-app if it turns out that you and someone else 'like' each other's profiles. The app is super buggy at the moment, but it's a neat idea worth checking out if online dating is your scene.

SendHub from InfoReach is the latest in a long line of apps that seek to make business communications easier, while also keeping your personal number as personal as possible. Offering a voice over internet alternative phone service, you can make a free business line in any area code, text and call right from the app, plus enjoy nifty features like call forwarding, group texting, voicemail, and the rest. It's also got a few bugs skittering about in its system, but it works quite well as is, and is definitely a great place to look if you want to keep your business and personal lives separate.


Best Educational Apps, Handpicked By Experts

Appolicious is pleased to introduce appoLearning.com, where parents, teachers and students find great education apps. Check out our introduction video here!


Source: http://www.androidapps.com/tech/articles/13432-one-today-by-google-leads-android-apps-of-the-week

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Chevron profit down 4.5 pct. on lower oil prices

FILE - This April 21, 2008 file photo shows a Chevron flag flying over the Chevron refinery in Richmond, Calif. Chevron Corp. reports quarterly financial results before the market opens on Friday, April 26, 2013. (AP Photo/Ben Margot, File)

FILE - This April 21, 2008 file photo shows a Chevron flag flying over the Chevron refinery in Richmond, Calif. Chevron Corp. reports quarterly financial results before the market opens on Friday, April 26, 2013. (AP Photo/Ben Margot, File)

In this Thursday, Apr. 25, 2013, photo, Los Angeles Police police officers fill up at a Chevron gas station downtown Los Angeles. Chevron Corp. reports quarterly financial results before the market opens on Friday, April 26, 2013. (AP Photo/Damian Dovarganes)

In this Thursday, Apr. 25, 2013, photo, the logo of Chevron is seen at a gas station downtown Los Angeles. Chevron Corp. reports quarterly financial results before the market opens on Friday, April 26, 2013. (AP Photo/Damian Dovarganes)

In this Thursday, Apr. 25, 2013, photo, the logo of Chevron is seen at a gas station downtown Los Angeles. Chevron Corp. reports quarterly financial results before the market opens on Friday, April 26, 2013. (AP Photo/Damian Dovarganes)

(AP) ? Chevron Corp.'s net income fell 4.5 percent in the first quarter as oil prices fell and refinery output declined.

Chevron, the second largest U.S. oil company, has delivered better profit margins than the other energy majors in recent years because a big part of its production mix is oil, which has been fetching high prices. Rivals, like Exxon Mobil, produce more natural gas in the U.S, where gas prices have been low.

But crude prices fell across the globe in the first three months of this year as Europe remained mired in recession and growth in China slowed. That reduced Chevron's revenue and profit.

Chevron, based in San Ramon, Calif., reported Friday that net income fell to $6.18 billion, or $3.18 per share, on revenue of $56.82 billion. Last year the company earned $6.47 billion, or $3.27 per share, on revenue of $60.71 billion.

The profit exceeded analysts' average forecast of $3.09 per share. Shares rose 84 cents to $119.35 in midday trading Friday.

Chevron did manage to boost production, although just slightly. Output of oil and gas rose to 2.65 million barrels per day from 2.63 million barrels per day in last year's quarter.

But Chevron's average sale price for a barrel of oil slipped to $94 from $102 last year in the U.S., and to $102 from $110 abroad. Natural gas prices edged up around the world, but not enough to offset the decline in oil prices.

Chevron hopes to increase production by 25 percent to 3.3 million barrels per day by 2017. The company is developing 50 projects that will each cost it $250 million or more, and 16 that will cost at least $1 billion each.

Production at Chevron's bigger rival Exxon Mobil has been slipping, but Exxon produced 4.4 million barrels per day in the first quarter, two-thirds more than Chevron.

Chevron's has been partly constrained by the shutdown shut production at an offshore Brazil platform after two spills last year. Earlier this month, Brazilian regulators gave Chevron permission to restart production.

Pat Yarrington, Chevron's chief financial officer, told investors Friday that the operation in Brazil's Frade field would restart in the second quarter, but that it would ramp up slowly and contribute only about 5,000 barrels per day this year.

Yarrington said a liquefied natural gas project in Angola will also begin operating in the second quarter and will add 20,000 barrels per day in production this year, then 60,000 barrels per day next year.

Performance at Chevron's refining operations slipped because of maintenance and upgrades at refineries in El Segundo, Calif. and Pascagoula, Miss. and continued repairs at its Richmond Calif. refinery in the wake of an August fire.

Refinery output fell 38 percent to 576,000 barrels per day.

"It was just a very heavy first quarter maintenance schedule this year," Yarrington said. She said output will be "substantially back" in the second quarter.

Yarrington said the El Segundo and Pascagoula refineries are operating at normal levels again. The Richmond refinery has begun taking in crude and is expected to restart in the second quarter.

Brian Youngberg, an analyst at Edward Jones, said Chevron's disappointing U.S. refining results were the only "hiccup" in an otherwise solid quarter.

Follow Jonathan Fahey on Twitter at http://twitter.com/JonathanFahey .

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-04-26-US-Earns-Chevron-2nd-Ld-Writethru/id-46bf4a4674bd4444aba0a973ea82cda9

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'Open' Season in High Tech - NYTimes.com

Things must be getting really competitive in high technology. So many big competitive companies are striving to show how good they are at sharing.

In particular, they share the word ?open.? In the world of cloud computing, we now have OpenFlow switching specification; the OpenStack cloud platform; Open Compute, dedicated to efficient computing infrastructure; the Open Virtualization Alliance, to create software that makes one computer server do the work of many; and OpenDaylight, to generate similar magic on computer networks.

For good measure, there is also the Open Grid Forum, which works on large-scale corporate and scientific computing, and the Open Cloud Consortium, which backs cloud computing for scientific and medical research.

That pattern you may have noticed in the names is no accident. By calling your group ?open? in tech, you intimate that you believe in the free sharing of information to create superior products. It evokes the open source spirit that made the Linux operating system, as well as less-known Internet standards like the Apache Web server, so successful.

Just as important, for public relations purposes, it suggests that companies not in the group should be suspect, as they do not support that sharing, let-everything-be-free sensibility. If they are not outwardly open, they must be closed.

That is a useful message for a big incumbent player trying to combat an upstart that is threatening the incumbent?s business. Hewlett-Packard, Cisco Systems and Brocade, which for years made proprietary network switches, supported a recent meeting of OpenFlow. H.P. is also in the Open Virtualization, OpenStack and OpenDaylight groups. Cisco is also in OpenDaylight and the Open Cloud Consortium, while Intel is on the board of Open Compute and belongs to Open Virtualization and OpenDaylight.

There are many other such corporate affiliations throughout these groups. Among these many interests, it should be noted, the Open Cloud Initiative does not accept corporate sponsorship.

It may be, of course, that despite running large legal departments that vigilantly look after their company?s intellectual property, these multibillion-dollar companies have bought into the philosophy of open source ? that all software should be free. If so, the shareholders should probably be told.

Or, more pragmatically, it may be that the big businesses? products and services are threatened by new software-driven companies. In that case, it makes sense to donate some of the less valuable parts, collaborate together and try to swarm the upstarts with something better.

The fact that Amazon.com, the leader in public clouds, is not in any of the ?open? cloud organizations points at who the real competition is. Likewise, VMware, which significantly lowered the value of an individual server by pioneering virtualization, does not belong to Open Virtualization.

The pragmatic reading ? that the incumbents are motivated by expedience more than a desire to share ? is perfectly fine. It is business, leveraging as many people as possible in an open source project to undermine what the competition is doing.

But it would be O.K. if they were open about that, too.

Source: http://bits.blogs.nytimes.com/2013/04/26/open-season-in-high-tech/

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Already down 0-2 to Spurs, Lakers injuries mount

AAA??Apr. 25, 2013?4:43 PM ET
Already down 0-2 to Spurs, Lakers injuries mount
By GREG BEACHAM?THE ASSOCIATED PRESS STATEMENT OF NEWS VALUES AND PRINCIPLES?By GREG BEACHAM

Los Angeles Lakers' Steve Nash (10) drives to the basket as San Antonio Spurs' Tony Parker, right, of France, defends him during the second half of Game 2 of a first-round NBA basketball playoff series, Wednesday, April 24, 2013, in San Antonio, Texas. San Antonio won 102-91. (AP Photo/Eric Gay)

Los Angeles Lakers' Steve Nash (10) drives to the basket as San Antonio Spurs' Tony Parker, right, of France, defends him during the second half of Game 2 of a first-round NBA basketball playoff series, Wednesday, April 24, 2013, in San Antonio, Texas. San Antonio won 102-91. (AP Photo/Eric Gay)

Los Angeles Lakers' Steve Blake (5) passes to teammate Dwight Howard (12) as he is pressured by San Antonio Spurs' Matt Bonner, left, and Tim Duncan, second from right, during the second half of Game 2 of a first-round NBA basketball playoff series, Wednesday, April 24, 2013, in San Antonio, Texas. San Antonio won 102-91. (AP Photo/Eric Gay)

San Antonio Spurs' Tony Parker, right, of France, drives as Los Angeles Lakers' Steve Nash (10) defends during the first half of Game 2 of a first-round NBA basketball playoff series on Wednesday, April 24, 2013, in San Antonio, Texas. (AP Photo/Eric Gay)

San Antonio Spurs' Tim Duncan (21) is defended by Los Angeles Lakers' Dwight Howard (12) while trying to score during the first half of Game 2 of a first-round NBA basketball playoff series on Wednesday, April 24, 2013, in San Antonio, Texas. (AP Photo/Eric Gay)

San Antonio Spurs' Tony Parker (9), of France, drives to the basket as he is defended by Los Angeles Lakers' Earl Clark (6) during the second half of Game 2 of a first-round NBA basketball playoff series, Wednesday, April 24, 2013, in San Antonio, Texas. San Antonio won 102-91. (AP Photo/Eric Gay)

EL SEGUNDO, Calif. (AP) ? Steve Blake won't play for the Los Angeles Lakers in Game 3 against the San Antonio Spurs on Friday, and fellow guards Steve Nash and Jodie Meeks are doubtful.

The Lakers are running out of healthy guards, and they're increasingly out of ideas on how to stop the Spurs from ending their tumultuous season.

Blake has a strained right hamstring that will keep him out indefinitely, and coach Mike D'Antoni said Thursday that the backup point guard won't play in Game 3.

Nash got two epidural injections in his back and a cortisone injection in his right hip in an attempt to fight off his nagging pain.

D'Antoni says Nash is more likely to play than Meeks, who has a sprained left ankle.

Kobe Bryant is out for the season.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2013-04-25-BKN-Spurs-Lakers/id-de2d989173894152a61d163849e5cd6f

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Help 'Bobby Ewing' and homeless pets in West by adopting from ...

Bobby Ewing is looking for a forever home with a big yard (he promises not to drill for oil in it) (Operation Kindness)

Hundreds of pets have lost their homes as a result of the April 17 fertilizer plant explosion in West Texas. Operation Kindness in Carrollton, the largest no-kill shelter in North Texas, is working with the Humane Society of Central Texas?in Waco, to find them forever homes.

The best way to help is by fostering or adopting some of the beautiful dogs and cats at Operation Kindness like Bobby Ewing (a?lab/Great Pyrenees mix)?or Felicia (a domestic shorthair mix) which will open up space for the pets that are being moved from West to the Waco City Shelter and from the Waco City Shelter to Carrollton. Operation Kindness cares for an average of 300 animals at the shelter daily, with more than 100 in foster homes.

If you?re thinking of adopting, Operation Kindness is offering $25 off fees through April 30 for those who sign a pledge against cruelty to animals as our?Joy Tipping has reported; ?in addition to going to the shelter itself at 3201 Earhart Drive, Carrollton (972-418-PAWS), there?s also a Saturday adoption event from 11 am. to 3 p.m. at FETCH! at Ebby Halliday Realtors, 5999 Northwest Holiday at Preston Road, Dallas.

If your home is too full but there?s still room in your heart, money or gift cards are appreciate for Operation Kindness or to the Humane Society of Central Texas (call 254-754-1454 and?be careful to make sure your donations are going to the right place and not to fraudulent sites masquerading as charities).

Here are some of the beauties looking for their forever homes:

Oliver and Olivia

Oliver & Olivia (Olivia is in the pink collar) are from the Waco shelter. Olivia is 1 year old and weighs 5.7 lbs. Oliver is 2 years old and weighs 4.3 pounds. They are Chihuahua/Affenpinscher mix.

Bobby Ewing is a year-old lab/Great Pyrenees mix who was found as a stray in January. He is just over a year old and weighs 60 pounds. He is good with kids and has lots of energy. He would love a good home with a big yard. (He promises not to drill for oil in the yard, too).

Felicia

Felicia is a two-and-a-half year old domestic, shorthair mix with beautiful markings and hypnotic eyes who was abandoned at?Operation?Kindness?with a kitty friend. They were left outside the shelter in a box all night, so they were frightened and nervous when they arrived, but they?ve come a long way since then.??She is a quiet, sweet lap cat who would be ideal for single adults and couples without children.

Buck, Rosie, Benjamin, Sammy and UB

Buck, Rosie, Benjamin, Sammy and UB?are 2-month-old?Chihuahua mix puppies. They?just came back to the shelter from foster care and are ready for their forever homes.

Orco

Orco is a 10-month-old domestic, shorthair mix with a loving and affectionate disposition. ?Orco was found as a stray and taken in by a kind citizen. Arrangements were made and he was brought to?Operation?Kindness?for a fresh start. Orco is a fun, playful kitten who loves everyone: kids, adults, other cats ? he?s even good with dogs.

Source: http://dallaslifeblog.dallasnews.com/2013/04/help-bobby-ewing-and-homeless-pets-in-west-by-adopting-from-operation-kindness-in-carrollton.html/

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April 24th, 2013 by Martin

Israeli focus on Syria gives Hagel respite on Iran

JERUSALEM (AP) ? On Chuck Hagel's inaugural visit to Israel as U.S. defense secretary, Syria surpassed Iran as the security threat of greatest urgency to the U.S.' closest Mideast ally. That quite unexpectedly gave the new Pentagon chief a temporary respite from the delicate duty of tempering Israeli warnings about attacking Iran to stop it from building a nuclear bomb.

Israeli leaders see Iran's nuclear ambitions as a threat to their country's very existence, given Tehran's vow to wipe it off the map. But Syria suddenly has emerged so prominently that it overshadowed Iran during Hagel's three days in Israel.

That explains, in part, why Hagel repeatedly stressed in public Israel's right to defend itself and to decide on its own, if necessary, whether and when to attack Iran. He gave less emphasis than usual by American officials to Washington's wish that diplomacy and sanctions be given more time to persuade Iran to change course.

Notably, Israel's new defense minister, Moshe Yaalon, said at a joint news conference with Hagel on Monday that he, too, thinks non-military means ought to be pursued further.

"By one way or another, the military nuclear project of Iran should be stopped," Yaalon said. "Having said that, we believe that the military option, which is well discussed, should be the last resort anyhow." He added, "There are other tools to be used and to be exhausted, whether it is diplomacy, economic sanctions, or even more support of the opposition in Iran."

Hagel seemed to sense slightly less urgency in the Israeli concern about Iran, although he by no means dismissed the problem. One year ago, Hagel's predecessor, Leon Panetta, was letting it be known that he feared Israel could attack Iran in a matter of weeks. Washington worries that such a strike could ignite a wider war in which it would be difficult for the U.S. to avoid getting involved.

That was before the Syrian civil war had reached the point of widespread concern that its illicit stockpiles of chemical weapons could pose a threat to Israel and other neighbors.

Jordan, too, is worried about transfers of Syrian chemical weapons. Hagel stopped briefly in Jordan Tuesday.

"The United States and Jordan share mutual concerns about the ongoing crisis in Syria and continue to consult closely on a number of issues including chemical weapons and the demands posed by the influx of Syrian refugees fleeing the violence," Pentagon press secretary George Little said after Hagel's meeting in Amman.

Little said the Pentagon has provided more than $70 million to Jordan this year to help secure its border and prevent the transfer of chemical weapons from Syria.

Hagel ended his day in Riyadh, Saudi Arabia, where he met with Crown Prince Salman bin Abdulaziz al-Saud, who also serves as the Saudi defense minister. Little said they discussed a proposed sale of advanced U.S. missiles for Saudi F-15 fighters as well as mutual concerns about Iran's nuclear program and the violence in Syria.

The Israelis see immediate dangers in the Syrian civil war, not only in the threat along Israel's northeastern border but also in the grim possibility that Syrian chemical weapons could fall into the hands of extremists. Israel says each of those possibilities is a "red line" beyond which it would have to act.

The concern is that if President Bashar Assad is overthrown, any of the Islamic extremist groups trying to oust him could turn his extensive arsenal against Israel.

A senior Israeli military intelligence official said Tuesday that Assad has repeatedly used chemical weapons against insurgent groups. It was the first such public claim by Israel and appeared to increase pressure on Washington and other Western countries to intervene in Syria.

President Barack Obama has warned that the use of chemical weapons by Assad would be a "game changer." Little, the Pentagon press secretary, said Tuesday the U.S. government is still assessing reports of Syrian chemical weapons use, adding that such acts would be "entirely unacceptable." He did not elaborate on possible U.S. actions.

The White House said Tuesday the U.S. hasn't yet come to the conclusion that Assad has used chemical weapons even though close U.S. allies say he has.

In his assessment, Brig. Gen. Itai Brun, the head of research and analysis in Israeli military intelligence, told a security conference in Tel Aviv that Assad has used chemical weapons multiple times, including near Damascus, the capital, last month.

During Hagel's visit, Israeli leaders still emphasized the dangers of a nuclear-armed Iran ? as did Hagel. But to a degree not foreseen when Hagel arrived in Israel over the weekend, the threat posed by Syria's chemical weapons overshadowed Iran.

Hagel wrapped up his visit Tuesday by meeting with Prime Minister Benjamin Netanyahu, who greeted him with a brief but pointed caution about resolving the Iran problem. He complained of Iran arming terrorist groups with sophisticated weapons, and its "attempt to arm itself with nuclear weapons."

"This is a challenge that Israel cannot accept, and as you and President Obama have repeatedly said, Israel must be able to defend itself, by itself, against any threat," Netanyahu said.

___

Associated Press writer Ariel David contributed to this report.

Robert Burns can be followed on Twitter at http://www.twitter.com/robertburnsAP

Source: http://news.yahoo.com/israeli-focus-syria-gives-hagel-respite-iran-190331708--politics.html

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After brain injury, new astrocytes play unexpected role in healing

Apr. 24, 2013 ? The production of a certain kind of brain cell that had been considered an impediment to healing may actually be needed to staunch bleeding and promote repair after a stroke or head trauma, researchers at Duke Medicine report.

These cells, known as astrocytes, can be produced from stem cells in the brain after injury. They migrate to the site of damage where they are much more effective in promoting recovery than previously thought. This insight from studies in mice, reported online April 24, 2013, in the journal Nature, may help researchers develop treatments that foster brain repair.

"The injury recovery process is complex," said senior author Chay T. Kuo, M.D., PhD, George W. Brumley Assistant Professor of Cell Biology, Pediatrics and Neurobiology at Duke University. "There is a lot of interest in how new neurons can stimulate functional recovery, but if you make neurons without stopping the bleeding, the neurons don't even get a chance. The brain somehow knows this, so we believe that's why it produces these unique astrocytes in response to injury."

Each year, more than 1.7 million people in the United States suffer a traumatic brain injury, according to the Centers for Disease Control and Prevention. Another 795,000 people a year suffer a stroke. Few therapies are available to treat the damage that often results from such injuries.

Kuo and colleagues at Duke are interested in replacing lost neurons after a brain injury as a way to restore function. Once damaged, mature neurons cannot multiply, so most research efforts have focused on inducing brain stem cells to produce more immature neurons to replace them.

This strategy has proved difficult, because in addition to making neurons, neural stem cells also produce astrocytes and oligodendrocytes, known as glial cells. Although glial cells are important for maintaining the normal function of neurons in the brain, the increased production of astrocytes from neural stem cell has been considered an unwanted byproduct, causing more harm than good. Proliferating astrocytes secrete proteins that can induce tissue inflammation and undergo gene mutations that can lead to aggressive brain tumors.

In their study of mice, the Duke team found an unexpected insight about the astrocytes produced from stem cells after injury. Stem cells live in a special area or "niche" in the postnatal/adult brain called the subventricular zone, and churn out neurons and glia in the right proportions based on cues from the surrounding tissue.

After an injury, however, the subventricular niche pumps out more astrocytes. Significantly, the Duke team found they are different from astrocytes produced in most other regions of the brain. These cells make their way to the injured area to help make an organized scar, which stops the bleeding and allows tissue recovery.

When the generation of these astrocytes in the subventricular niche was experimentally blocked after a brain injury, hemorrhaging occurred around the injured areas and the region did not heal. Kuo said the finding was made possible by insights about astrocytes from Cagla Eroglu, PhD, whose laboratory next door to Kuo's conducts research on astrocyte interactions with neurons.

"Cagla and I started at Duke together and have known each other since our postdoctoral days," Kuo said. "To have these stem cell-made astrocytes express a unique protein that Cagla understands more than anyone else, it's just a wonderful example of scientific serendipity and collaboration."

Additionally, Kuo said first author Eric J. Benner, M.D., PhD, a former postdoctoral fellow who now has his own laboratory at Duke, provided key clinical correlations on brain injury as a physician-scientist and practicing neonatologist in the Jean and George Brumley Jr. Neonatal-Perinatal Research Institute.

"We are very excited about this innate flexibility in neural stem cell behavior to know just what to do to help the brain after injury," Kuo said. "Since bleeding in the brain after injury is a common and serious problem for patients, further research into this area may lead to effective therapies for accelerated brain recovery after injury."

In addition to Kuo, Eroglu and Benner, authors include Dominic Luciano, Rebecca Jo, Khadar Abdi, Patricia Paez-Gonzalez, Huaxin Sheng, David Warner and Chunlei Liu.

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Story Source:

The above story is reprinted from materials provided by Duke University Medical Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Eric J. Benner, Dominic Luciano, Rebecca Jo, Khadar Abdi, Patricia Paez-Gonzalez, Huaxin Sheng, David S. Warner, Chunlei Liu, Cagla Eroglu, Chay T. Kuo. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature, 2013; DOI: 10.1038/nature12069

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/zIrBOIqCR0I/130424132707.htm

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